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Upper gastrointestinal tract bleeding management : Belgian guidelines for adults and children

Journal Volume 74 - 2011
Issue Fasc.1 - Expert Point of View
Author(s) I. Colle, A. Wilmer, O. Le Moine, R. Debruyne, J. Delwaide, E. Dhondt, E. Macken, A. Penaloza, H. Piessevaux, X. Stéphenne, S. Van Biervliet, P.-F. Laterre
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(1) Department of Hepatology and Gastroenterology, Ghent University Hospital, Ghent, Belgium ; (2) Department of Medical Intensive Care Unit, Leuven University Hospital Gasthuisberg, Leuven, Belgium ; (3) Department of Hepatology and Gastroenterology, Université Libre de Bruxelles ULB Erasme, Anderlecht, Belgium ; (4) Department of Pediatric Hepatology and Gastroenterology, Ghent University Hospital, Ghent, Belgium ; (5) Department of Hepatology and Gastroenterology, Liège University Hospital, Liège, Belgium ; (6) Department of Emergency and Disaster Medicine, Universitair Ziekenhuis Brussel, Brussels, Belgium ; (7) Department of Hepatology and Gastroenterology, Antwerp University Hospital, Antwerp, Belgium ; (8) Emergency Department, Catholic University Hospital of Brussels, UCL, Brussels, Belgium ; (9) Department of Hepatology and Gastroenterology, Catholic University Hospital of Brussels, UCL, Brussels, Belgium ; (10) Department of Pediatric Hepatology and Gastroenterology, Catholic University Hospital of Brussels, UCL, Brussels, Belgium ; (11) Department of Intensive Care, Catholic University Hospital of Brussels, UCL, Brussels, Belgium.

Upper gastrointestinal bleeding (UGIB) remains a common dis- ease affecting 100 to 170 per 100 000 adults per year and causing thereby a significant burden to healthcare resources. Despite the improvements in the management of this disorder, the associated mortality ranges from 5 to 14%. Since the general management of UGIB is not uniform, the main objective of this work is to provide guidelines for the care of adults and children presenting with bleeding caused by gastro-duodenal ulcer or variceal rupture. Methods : In the absence of evidence-based recommendations, these guidelines were proposed after expert opinions reconciliation and graded accordingly. They are based on the published literature up to September 2010 and graded according to the class of evidence. Results : The current guidelines for the management of UGIB include recommendations for the diagnostic process, general sup- portive care, pharmacological therapy aiming at bleeding control, specific and endoscopic treatment of acute bleeding and follow-up for both gastro-duodenal ulcers and portal hypertension-induced bleeding. (Acta gastroenterol. belg., 2011, 74, 45-66).

© Acta Gastro-Enterologica Belgica.
PMID 21563653